Is the honeymoon period over for Microsoft and OpenAI? Strained relations and deals with competitors spell trouble for the partnership that transformed the AI industry
The two firms are slowly drifting apart as both forge closer ties with respective rivals
Microsoft and OpenAI have signed an agreement to shake up the duo’s long-running partnership at the latter looks to restructure into a for-profit company.
The move marks the latest development in a changing relationship dynamic for the two firms, with both forging ties with other industry stakeholders and respective competitors.
“Microsoft and OpenAI have signed a nonbinding memorandum of understanding (MOU) for the next phase of our partnership,” a joint statement reads. “We are actively working to finalize contractual terms in a definitive agreement.”
OpenAI's push to becoming a for-profit entity requires approval from Microsoft, as per the terms of their partnership. While the exact terms of the revised agreement are yet to be revealed, at this stage it appears to come with a notable caveat.
OpenAI revealed the nonprofit parent will still retain oversight of the company, taking an equity stake of around $100 billion.
In a follow-up statement, chairman Bret Taylor noted this makes it “one of the most well-resourced philanthropic organizations in the world”.
Microsoft and OpenAI were destined to clash
The proposed changes come as Microsoft and OpenAI continue to drift apart in key areas. It’s a talking point that’s become a recurring theme over the last year, with both companies now essentially competing for customers.
Sign up today and you will receive a free copy of our Future Focus 2025 report - the leading guidance on AI, cybersecurity and other IT challenges as per 700+ senior executives
In January, Microsoft told ITPro OpenAI “continues to be our partner on frontier models” following reports it was exploring the prospect of integrating third-party alternatives to power its Microsoft 365 Copilot service.
On 9 September, reports from The Information revealed Microsoft will now pay Anthropic to use its AI in Office 365 applications alongside OpenAI options. This will see Anthropic AI models used to power a host of key applications, including Word, Excel, Outlook, and PowerPoint.
OpenAI has also made moves to distance itself from Microsoft, largely on the issue of compute power. The company is a key figure in the $500 billion Stargate Project alongside Oracle and SoftBank, for example, which aims to build out AI infrastructure across the United States.
In January, OpenAI also moved away from using Microsoft Azure as its sole cloud provider, and has been forging closer ties with Oracle. A June 2024 agreement saw Oracle, Microsoft, and OpenAI partner to "provide additional capacity” for the latter.
This included using the Azure AI platform on Oracle Cloud Infrastructure (OCI) for “inference and other needs”, the company said at the time.
This partnership fueled speculation about an emerging rift with Microsoft, prompting OpenAI to issue a statement claiming its “strategic cloud relationship with Microsoft is unchanged”.
OpenAI’s for-profit conundrum
OpenAI has faced significant pushback in its shift to become a for-profit entity.
In December 2024, the company proposed establishing itself as a Public Benefit Corporation (PBC). This would mean the nonprofit will hold shares in the company but have little influence.
A second push to split commercial operations and become a for-profit company was scrapped in May following pressure from industry stakeholders, regulators, and former employees such as Elon Musk.
The Tesla and SpaceX chief executive filed a legal challenge to block the move, claiming it disregarded and ran counter to the company’s founding principles.
In a blog post at the time, OpenAI confirmed the nonprofit would “stay in control after hearing from civic leaders and having discussions with the offices of the Attorneys General of California and Delaware”.
Make sure to follow ITPro on Google News to keep tabs on all our latest news, analysis, and reviews.
MORE FROM ITPRO

Ross Kelly is ITPro's News & Analysis Editor, responsible for leading the brand's news output and in-depth reporting on the latest stories from across the business technology landscape. Ross was previously a Staff Writer, during which time he developed a keen interest in cyber security, business leadership, and emerging technologies.
He graduated from Edinburgh Napier University in 2016 with a BA (Hons) in Journalism, and joined ITPro in 2022 after four years working in technology conference research.
For news pitches, you can contact Ross at ross.kelly@futurenet.com, or on Twitter and LinkedIn.
-
Enterprise AI adoption is about to get the Big Brother treatmentOpinion Worried your staff aren’t using those shiny AI tools you petitioned for? Big tech has you covered
-
Dreamforce 2025: What's an agentic OS?ITPro Podcast NPUs, e-ink, and immersive headsets are the latest hardware innovations for business devices
-
'It's slop': OpenAI co-founder Andrej Karpathy pours cold water on agentic AI hype – so your jobs are safe, at least for nowNews Despite the hype surrounding agentic AI, OpenAI co-founder Andrej Karpathy isn't convinced and says there's still a long way to go until the tech delivers real benefits.
-
Nvidia CEO Jensen Huang says future enterprises will employ a ‘combination of humans and digital humans’ – but do people really want to work alongside agents? The answer is complicated.News Enterprise workforces of the future will be made up of a "combination of humans and digital humans," according to Nvidia CEO Jensen Huang. But how will humans feel about it?
-
‘I don't think anyone is farther in the enterprise’: Marc Benioff is bullish on Salesforce’s agentic AI lead – and Agentforce 360 will help it stay top of the perchNews Salesforce is leaning on bringing smart agents to customer data to make its platform the easiest option for enterprises
-
This new Microsoft tool lets enterprises track internal AI adoption rates – and even how rival companies are using the technologyNews Microsoft's new Benchmarks feature lets managers track and monitor internal Copilot adoption and usage rates – and even how rival companies are using the tool.
-
Salesforce just launched a new catch-all platform to build enterprise AI agentsNews Businesses will be able to build agents within Slack and manage them with natural language
-
The tech industry is becoming swamped with agentic AI solutions – analysts say that's a serious cause for concernNews “Undifferentiated” AI companies will be the big losers in the wake of a looming market correction
-
Microsoft says 71% of workers have used unapproved AI tools at work – and it’s a trend that enterprises need to crack down onNews Shadow AI is by no means a new trend, but it’s creating significant risks for enterprises
-
OpenAI signs another chip deal, this time with AMDnews AMD deal is worth billions, and follows a similar partnership with Nvidia last month